Thursday, August 21, 2008
i finally showered n reading up pharmacology
so this is the latest updates on how much i noe on pharmacology
lets start from the beginning
3 types for classification of drugs:
theraputic (antihypertensive)
pharmacologic (diuretics,ACE inhibitor, calcium channel blockers)
poison (POM, P, P+ POM, G)
3 types for naming a drug (drug nomenclature)
chemical name
generic name
trade name
Pharmokinetics: deals with what happen to the drugs throughout the body.
Consists of 4 major components which are Absorption, Distribution, Metabolisation, Excretion.
Absoprtion: rate and extent by which the drug moves from the site of administration.
It is affected by route of administration, blood flow, surface area available, physical nature of drug dosage, presence of food in the stomach, concurrent oral administration of other drugs, solubility of the drugs.
Bioavailability: the fraction of the administered drug that is absorbed.
Distribution: the process by which the drugs leaves the bloodstream and enters into the cells of the tissue.
3 primary processes: active transport, passive diffusion and via carrier proteins.
These processes are affected by blood flow, permeability of the capillary, binds to plasma proteins and drug structure.
Metabolism: refers to the biological transformation of a drug into an inactive/ more potent metabolite.
Main organ: Liver
Mechanism: oxidation, reduction
Factors affecting metabolization: genetics, environment, age, nutrition and diseaseas.
Excretion: process by which the drug or metabolite is removed from the body
Main organ: Kidney
Mechanism: glomerular filtration, tubular secretion.
tats all i manage to remember on the initial part of the book.
not to mention the drugs from the various groups. damn damn
toodles
Labels: pharmacology
perspective
2:23 PM
